Comparative study between lateral versus latero-ventral quadratus lumborum block for perioperative analgesia in canine laparoscopic ovariectomy

Originally Published hereTo compare the perioperative analgesic effect of lateral versus latero-ventral quadratus lumborum block (QLB) in dogs undergoing laparoscopic ovariectomy.

Distinct Synaptic Vesicle Proteomic Signatures Associated with Pre- and Post-Natal Oxycodone-Exposure

Originally Published hereThe current opioid crisis, which has ravaged all segments of society, continues to pose a rising public health concern. Importantly, dependency on prescription opioids such as oxycodone (oxy) during and after pregnancy can significantly impact the overall brain development of the exposed offspring, especially at the synapse. A significant knowledge gap that remains…

Pharmacokinetics of methadone after intravenous and subcutaneous administration in domestic ferrets (Mustela putorius furo)

Originally Published hereTo determine the pharmacokinetic profile of methadone after intravenous (IV) and subcutaneous (SC) administration in domestic ferrets (Mustela putorius furo).

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Neuromodulation Techniques for Chronic Pain Management: Efficacy and Insights

Originally Published hereIn recent years, there has been a growing interest in the use of neuromodulation as an alternative treatment option for chronic pain. Neuromodulation techniques, such as spinal cord stimulation (SCS), dorsal root ganglion (DRG) stimulation, deep brain stimulation (DBS), and peripheral nerve stimulation, have shown promising results in the management of various chronic…

Improving Ventilation in Anesthetized Pigs: Impact of Adding a Second APL Valve on Breathing Effectiveness

Originally Published hereSpontaneous breathing of pigs during general anaesthesia may not be very effective. This may be related to the chest wall elastance and marked tendency of the lung to collapse in young pigs (Liu et al 1999). Resistance of the breathing system may also contribute to poor ventilation by increasing the work of breathing….