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Serum tryptase changes in children with suspected perioperative hypersensitivity. Comment on BJA Open 2024; 9: 100254

Originally Published hereEditor—We read with interest the recent publication by Vlaeminck and colleagues.1 A dynamic change in the acute serum tryptase concentration (aST) from the basal serum tryptase concentration (bST) suggests mast cell degranulation and can be used to support a diagnosis of anaphylaxis. A new consensus formula, aST>bST+0.71, has been proposed by Vlaeminck and…

Comparative study between lateral versus latero-ventral quadratus lumborum block for perioperative analgesia in canine laparoscopic ovariectomy

Originally Published hereTo compare the perioperative analgesic effect of lateral versus latero-ventral quadratus lumborum block (QLB) in dogs undergoing laparoscopic ovariectomy.

Distinct Synaptic Vesicle Proteomic Signatures Associated with Pre- and Post-Natal Oxycodone-Exposure

Originally Published hereThe current opioid crisis, which has ravaged all segments of society, continues to pose a rising public health concern. Importantly, dependency on prescription opioids such as oxycodone (oxy) during and after pregnancy can significantly impact the overall brain development of the exposed offspring, especially at the synapse. A significant knowledge gap that remains…

Pharmacokinetics of methadone after intravenous and subcutaneous administration in domestic ferrets (Mustela putorius furo)

Originally Published hereTo determine the pharmacokinetic profile of methadone after intravenous (IV) and subcutaneous (SC) administration in domestic ferrets (Mustela putorius furo).

Code Snippets v No Code

When considering the appropriate approach to software development, the choice between utilizing code snippets and embracing a no-code solution can significantly influence both the speed and quality of the end product. Code snippets allow developers to leverage pre-existing code blocks for quick implementation, fostering a sense of efficiency and control over the final output. This…